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Alfa Aesar™ Puromycin dihydrochloride, 99%

Causes premature chain termination in protein synthesis

$88.82 - $948.41

Chemical Identifiers

CAS 58-58-2
Molecular Formula C22H31Cl2N7O5
Molecular Weight (g/mol) 544.434
MDL Number MFCD00012691
InChI Key MKSVFGKWZLUTTO-ZKWLAQDLSA-N
PubChem CID 131632508
IUPAC Name (2S)-2-amino-N-[(2S,3S,4S,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
SMILES CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61278MB View Documents Alfa Aesar™
J61278MB
25mg Each for $88.82
 
AAJ61278MC View Documents Alfa Aesar™
J61278MC
100mg Each for $268.32
 
AAJ61278ME View Documents Alfa Aesar™
J61278ME
500mg Each for $948.41
 
Description

Description

Applications
It also exhibits antitumor activity in studies on brain tumor cells. Puromycin is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3¢-terminal end of aminoacyl-tRNA. It has been used to study transcriptional regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.

Solubility
Soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications

Chemical Identifiers

58-58-2
544.434
MKSVFGKWZLUTTO-ZKWLAQDLSA-N
(2S)-2-amino-N-[(2S,3S,4S,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
C22H31Cl2N7O5
MFCD00012691
131632508
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl

Specifications

58-58-2
MFCD00012691
14,7943
MKSVFGKWZLUTTO-ZKWLAQDLSA-N
(2S)-2-amino-N-[(2S,3S,4S,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
131632508
Powder
White
25mg
C22H31Cl2N7O5
3853613
Soluble in water
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl
544.434
544.44
99%
168°C to 170°C
Puromycin dihydrochloride
Safety and Handling

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

GHS P Statement
P264-P270-P301+P312-P330-P501a
Wash thoroughly after handling.
Do not eat, drink or smoke when using this product.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : AU355000

Recommended Storage : −30° to −10°C