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Thermo Scientific™ ProSwift™ RP-4H LC Columns

Run fast protein separations at high linear velocities with Thermo Scientific™ ProSwift™ RP-4H LC Columns.

Manufacturer: thermo scientific™  069477

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Catalog No. DX069477


Description & Specifications


Column Type Reversed Phase
For Use With LC/MS
Type Analytical Column
Carbon Load -
Column Chemistry Phenyl
USP Type N/A
Endcapped -
Flow Rate 0.5mL/min.
Max. Pressure 2000psi
Packing Material Monolithic polymer
Particle Size Monolith
Temperature 70°C
Pore Size -
pH 1 to 14
Stationary Phase Phenyl
Solvents Most common Organic Solvents
Surface Area -
Length (Metric) 50mm
Description ProSwift RP-4H, medium channel
Column Format Analytical Column
Diameter (Metric) 1mm

Run fast protein separations at high linear velocities with Thermo Scientific™ ProSwift™ RP-4H LC Columns. These reversed-phase monolith columns deliver the outstanding resolving power of nonporous analytical media combined with faster separations and analysis than other bead-based columns. ProSwift polymer monolith columns in PEEK™ tubing achieve long column lifetime, excellent reproducibility even after hundreds of runs and have broad pH stability, providing high stringent wash capability (1M NaOH).

Each monolith is a single cylindrical polymer rod containing an uninterrupted, interconnected network of flow-through channels of a specific pore size. These large channels and the monolith's nonporous surfaces provide fast mass transfer for the high-resolution and fast protein separations. The monolith morphology results in low operating backpressure, allowing the use of higher linear velocities with minimal loss of resolution.

Advantages of High Resolution at Exceptionally High Flow Rates

  • Highest operational flow rates available
  • High throughput and improved productivity
  • Excellent stability over a wide pH range of 1 to 14
  • Outstanding reproducibility and ruggedness
  • High loading capacity
Fast, Sensitive Protein Separations
  • High speed protein separations
  • High sensitivity for LC-MS
  • High column-to-column reproducibility
  • Wide range of column I.D. and lengths available
  • Superior lifetime
Easy Column Installation
  • Use Thermo Scientific™ Dionex™ nanoViper™ Fingertight Fittings
Preconcentrate and Desalt Samples   
  • Precolumns are available to preconcentrate and desalt samples.
  • You can also use Thermo Scientific™ PepSwift™ Trap Columns for preconcentration and desalting of samples consisting of peptides and proteins without negatively impacting the chromatographic performance or recovery of the compounds.
  • Change the selectivity of the separation or improve the trapping efficiency by employing various ion-pairing agents in the loading solvent and/or mobile phases.