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Propargyl bromide, 80% in toluene, stab. with MgO, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A16580AU
Description
Propargyl bromide, 80% in toluene is used to prepare betulonic acid-peptide conjugates with anti-inflammatory activity and propargylic amines employed in enyne metathesis. It finds application in the propargylation of spiro ketones, allylic alcohols and enone complexes. In Barbier-type reaction, it reacts with aldehydes to give alkyne alcohols. It is actively involved in the synthesis of polyethylene glycol (PEG) and peptide-grafted polyesters.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsPropargyl bromide, 80% in toluene is used to prepare betulonic acid-peptide conjugates with anti-inflammatory activity and propargylic amines employed in enyne metathesis. It finds application in the propargylation of spiro ketones, allylic alcohols and enone complexes. In Barbier-type reaction, it reacts with aldehydes to give alkyne alcohols. It is actively involved in the synthesis of polyethylene glycol (PEG) and peptide-grafted polyesters.
Solubility
Miscible with ethanol, ether, benzene, carbon tetrachloride and chloroform. Immiscible with water.
Notes
Light sensitive. Store in a cool place. Incompatible withbases, strong oxidizing agents, copper, peroxides, silver, silver oxides, mercury and mercury oxides.
Specifications
Propargyl bromide | |
106-96-7 | |
1.335 | |
3°C (37°F) | |
1.494 | |
1000 mL | |
605309 | |
propargyl bromide, 3-bromopropyne, 3-bromo-1-propyne, 1-propyne, 3-bromo, 2-propynyl bromide, propynyl bromide, 1-bromo-2-propyne, propyne, 3-bromo, gamma-bromoallylene, 1-brom-2-propin | |
YORCIIVHUBAYBQ-UHFFFAOYSA-N | |
3-bromoprop-1-yne | |
7842 | |
80% in toluene |
stabilized with MgO | |
-61°C | |
88°C to 90°C | |
C3H3Br | |
MFCD00000241 | |
UN2924 | |
Light sensitive | |
Miscible with ethanol,ether,benzene,carbon tetrachloride and chloroform. Immiscible with water. | |
C#CCBr | |
118.961 | |
118.97 |
Chemical Identifiers
106-96-7 | |
118.961 | |
YORCIIVHUBAYBQ-UHFFFAOYSA-N | |
7842 | |
C#CCBr |
C3H3Br | |
MFCD00000241 | |
propargyl bromide, 3-bromopropyne, 3-bromo-1-propyne, 1-propyne, 3-bromo, 2-propynyl bromide, propynyl bromide, 1-bromo-2-propyne, propyne, 3-bromo, gamma-bromoallylene, 1-brom-2-propin | |
3-bromoprop-1-yne |
Safety and Handling
GHS H Statement
H225-H300-H304-H361-H373-H314-H335-H336
Highly flammable liquid and vapour.
Fatal if swallowed.
May be fatal if swallowed and enters airways.
Suspected of damaging fertility or the unborn child.
May cause damage to organs through prolonged or repeated exposure.
Causes severe skin burns and eye damage.
May cause respiratory irritation.
May cause drowsiness or dizziness.
P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
H225-H301-H304-H314-H335-H336-H361-H373
DOTInformation : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber : 203-447-1
RTECSNumber : UK4375000
TSCA : Yes
Recommended Storage : Keep cold
RUO – Research Use Only