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Thermo Scientific™ ProPac™ SCX-10 LC Columns


Separate protein variants in difficult matrices using ProPac SCX-10 LC Columns, which provide exceptionally high resolution.

Manufacturer: thermo scientific™  SP5522

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 Disclaimers

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.

Catalog No. DXSP5522

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Description & Specifications

Specifications

Temperature <60�C
Column Format Analytical Column
Diameter (Metric) 22mm
Particle Size 10µm
Column Type Ion Exchange
Packing Material Spherical, non-porous polymer
Mobile Phase Compatibility pH 2-12, 80% compatible with acetonitrile, acetone, methanol, compatible with nonionic and zwitterionic detergents, incompatible with cationic detergents
Max. Pressure 3000psi
For Use With HPLC
Column Construction PEEK
Stationary Phase Sulfonate
Carbon Load -
Flow Rate 1mL/min.
USP Type N/A
Resin Composition 10µm diameter core bead (55% cross-linked) grafted with a pellicular layer to which the sulfonate functional groups are attached
Technique Protein/Cation Exchange
Endcapped -
pH 2 to 12
Surface Area -
Pore Size Non-porous
Length (Metric) 250mm
Type Analytical Column

Separate proteins and their variants using Thermo Scientific™ ProPac™ SCX-10 LC Columns, which provide exceptionally high resolution. Based on stationary phases composed of 10µm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

  • Nonporous core particle results in high-efficiency peaks and high-resolution separations of protein variants
  • Hydrophilic layer prevents unwanted secondary interactions
  • Grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity
  • Useful for characterization of related protein variants