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Promega™ SGK1 Kinase Enzyme System

Optimized for use with ADP-Glo™ Kinase Assay to measure the activity of human SGK1 kinase

Manufacturer: promega™  V2911

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Catalog No. PRV2911


Description & Specifications


Molecular Weight 73
For Use With (Application) For both primary screening as well as Kinase selectivity profiling, promotes cell survival by Phosphorylating and inactivating FKHRL1
Quantity 10μg
Storage Requirements -20° to -70°C

SGK1 is a member of the serum- and glucocorticoid-induced protein kinase family that is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol (PI) 3-kinase. SGK1 mRNA is expressed in all tissues, and the level of SGK1 mRNA is increased by stimulation with serum or dexamethasone.

ADP-Glo Kinase Assay:

  • Luminescent assay that measures ADP formed from a kinase reaction
  • ADP is converted into ATP, which is a substrate in a reaction catalyzed by Ultra-Glo™ Luciferase that produces light
  • Luminescent signal positively correlates with ADP amount and kinase activity

Upon receipt, centrifuge the kinase and dispense it into smaller quantities.

ADP-Glo Kinase Assay: For both primary screening as well as kinase selectivity profiling