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Thermo Scientific™ Lab Vision™ Progesterone Receptor Ab-6, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Progesterone Receptor Ab-6, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS196P1ABX

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Catalog No. MS196P1ABX

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Description & Specifications

Specifications

Host Species Mouse
Applications Immunofluorescence
Applications Immunoprecipitation
Isotype IgG2b
Cross Reactivity Bovine
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Rabbit
Immunogen Partially purified PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice
Quantity 100µL
Format Concentrated
Regulatory Status RUO
Antigen Progesterone Receptor Ab-6
Clone hPRa 6
Research Discipline Cancer and Tumor Biology
Type Primary
Classification Monoclonal
Conjugate Unlabeled
Concentration 1mg/mL

Provide accurate, reproducible results with the Thermo Scientific™ Progesterone Receptor Ab-6, Mouse Monoclonal Antibody.

Human PgR exists in two forms: 116kDa (B-form) and 81kDa (A-form). It acts as ligand activated transcription factor to regulate expression of the target genes. Null mutation in PgR gene leads to pleiotrophic reproductive abnormalities.

Host Species: Mouse

Clone: hPRa 6

Isotype: IgG2b

Species Reactivity: Human, Cow, Rabbit, and Chicken. Does not react with monkey. Others not known.

Epitope: Not determined

Immunogen: Partially purified PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice

Molecular Weight: 116kDa (triplet, B-form)

Positive Control: T47D cells

Cellular Localization: Nuclear Ab-6 preferentially reacts with B-form of progesterone receptor.

Recommended for:

  • Western Blotting (Not optimum)
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Sedimentation in Sucrose Gradient

Note:

USA: RUO; Int'l: RUO