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Pokemon (LRF) Armenian Hamster anti-Human, Clone: 13E9, eBioscience™

Armenian Hamster Monoclonal Antibody

$143.55 - $288.55

Specifications

Antigen Pokemon (LRF)
Clone 1.30E+10
Host Species Armenian Hamster
Gene Alias Zbtb7a
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013022

 
affymetrix
14330982
100μg Each for $288.55

5013021

 
affymetrix
14-3309-80
25μg Each for $143.55
Description & Specifications

Specifications

Antigen Pokemon (LRF)
Clone 1.30E+10
Host Species Armenian Hamster
Gene Alias Zbtb7a
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This monoclonal antibody reacts with human Leukemia/lymphoma-related factor (LRF). This 65kDa protein is also known as POKEMON, FBI-1, and Zbtb7a. LRF is a member of the POK family of transcriptional repressors, and is expressed in hematopoietic stem cells, T and B lymphocytes, macrophages, and erythroid cells. This protein is also highly expressed in human non-Hodgkin’s lymphoma tissues and diffuse large B-cell lymphomas, demonstrating its prominent role in oncogenic transformation. Studies have demonstrated that LRF is also involved in B cell lineage commitment and development by opposing Notch signaling. Moreover, LRF is critical for erythroid terminal differentiation in the bone marrow by inhibiting Bim-mediated apoptosis. Finally, LRF interacts with Bcl-6 in germinal center B cells.