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Pokemon (LRF) Armenian Hamster anti-Human, Clone: 13E9, eBioscience™

Armenian Hamster Monoclonal Antibody

$130.68 - $262.68

Specifications

Antigen Pokemon (LRF)
Clone 1.30E+10
Host Species Armenian Hamster
Gene Alias Zbtb7a
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013022 Life Technologies
LS14330982
100μg Each for $262.68
5013021 Life Technologies
LS14330980
25μg Each for $130.68
Specifications

Description

This monoclonal antibody reacts with human Leukemia/lymphoma-related factor (LRF). This 65kDa protein is also known as POKEMON, FBI-1, and Zbtb7a. LRF is a member of the POK family of transcriptional repressors, and is expressed in hematopoietic stem cells, T and B lymphocytes, macrophages, and erythroid cells. This protein is also highly expressed in human non-Hodgkin’s lymphoma tissues and diffuse large B-cell lymphomas, demonstrating its prominent role in oncogenic transformation. Studies have demonstrated that LRF is also involved in B cell lineage commitment and development by opposing Notch signaling. Moreover, LRF is critical for erythroid terminal differentiation in the bone marrow by inhibiting Bim-mediated apoptosis. Finally, LRF interacts with Bcl-6 in germinal center B cells.
Description & Specifications

Specifications

Pokemon (LRF)
Armenian Hamster
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
1.30E+10
Zbtb7a
Immunohistochemistry (Formalin/Paraffin),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL