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Podoplanin Rat anti-Human, Clone: NZ-1.3, eBioscience™

Rat Monoclonal Antibody

$158.05 - $332.05

Specifications

Antigen Podoplanin
Clone NZ-1.3
Host Species Rat
Gene Alias PDPN
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122780

 
affymetrix
14938182
100μg Each for $332.05

5013816

 
affymetrix
14-9381-80
25μg Each for $158.05
Description & Specifications

Specifications

Antigen Podoplanin
Clone NZ-1.3
Host Species Rat
Gene Alias PDPN
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

Podoplanin is a 40kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2).

This antibody has been reported to block the interaction between Podoplanin and CLEC-2.