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Podoplanin Rat anti-Human, Clone: NZ-1.3, eBioscience™

Rat Monoclonal Antibody

$143.88 - $302.28

Specifications

Antigen Podoplanin
Clone NZ-1.3
Host Species Rat
Gene Alias PDPN
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122780 Life Technologies
LS14938182
100μg Each for $302.28
5013816 Life Technologies
LS14938180
25μg Each for $143.88
Specifications

Description

Podoplanin is a 40kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2).

This antibody has been reported to block the interaction between Podoplanin and CLEC-2.
Description & Specifications

Specifications

Podoplanin
Rat
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
NZ-1.3
PDPN
Immunohistochemistry (Formalin/Paraffin),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL