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Tocris™ PMX 464

Putative inhibitor of the Trx-TrxR system; antiproliferative

$186.36 - $782.69

Specifications

Product Type PMX 464
Inhibitors PMX 464
Molecular Weight 243.28
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

499610R

 
tocris™
4996/10
10mg Each for $186.36

499650R

 
tocris™
4996/50
50mg Each for $782.69
Description & Specifications

Specifications

Product Type PMX 464
Inhibitors PMX 464
Molecular Weight 243.28
Purity >98

Putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system. Shown to inhibit Trx and induce a G1/S block in HT29 cells; inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Also elicits an anti-inflammatory response in A549 cells.

  • Chemical Name: 4-(2-Benzothiazolyl)-4-hydroxy-2,5-cyclohexadien-1-one
  • Formula: C13H9NO2S
  • CAS Number: 485842-97-5
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >98