Thermo Scientific™ Lab Vision™ Plasminogen Ab-1, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ Plasminogen Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS659P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ Plasminogen Ab-1, Mouse Monoclonal Antibody.Plasminogen is a key proenzyme of plasmin in the fibrinolytic and thrombolytic systems, the deficiency of which leads to a mild thrombotic tendency. Plasminogen binds to fibrin as well as to the surface of endothelial cells and monocytes/macrophages, where it is activated to plasmin. Streptokinase is a plasminogen activator widely used in treating blood-clotting disorders. Complexes of streptokinase with human plasminogen can hydrolytically activate other plasminogen molecules to plasmin, which then dissolves blood clots. Apolipoprotein(a) is very similar to plasminogen in terms of amino acid sequence, it inhibits plasmin generation by competing with plasminogen's binding to fibrin and endothelial cells.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Human plasminogen protein
Molecular Weight: ∽120kDa
Positive Control: HUVEC cells
Cellular Localization: Secreted protein
- Western Blotting (Nonreduced only)
USA: RUO; Int'l: RUO
|Human plasminogen protein|