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Invitrogen™ PIK3CB/PIK3R1 (p110 beta/p85 alpha) Recombinant Human Protein DFS Item

PIK3CB/PIK3R1 (p110β/p85α) is a phosphoinositide-3-kinase (PI3K) comprised of a catalytic subunit, p110β, and a regulatory subunit, p85α, encoded by the PIK3CB and PIK3R1 genes respectively.

$2515.00 - $10880.00

Specifications

Accession Number NP_852664.1/NP_006210.1
For Use With (Application) Kinase Assay, Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
Formulation 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Gene ID (Entrez) PIK3CB, PIK3R1
Molecular Weight (g/mol) 84.7kDa/123.7kDa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
PV6455 DFS Item
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Invitrogen™
PV6455
100μg
Each for $2,515.00
 
PV6456 DFS Item
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Invitrogen™
PV6456
1mg N/A
N/A
Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description

Description

As with other members of the PI3K family, p110β has important regulatory roles in cellular processes including cell survival, proliferation, and differentiation. It affects growth factor signaling and survival by phosphorylating inositol lipids. PTEN-deficient cancer cells have been observed to depend on p110β signaling.

  • Available in 3 convenient sizes
  • Validated in our Adapta™ and Kinase Binding assays
  • A full-length protein that can help advance your research when used in validated assays
Specifications

Specifications

NP_852664.1/NP_006210.1
50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
84.7kDa/123.7kDa
Full Length, Recombinant, Active
PI3 Kinase
Recombinant
Baculovirus
Kinase Assay, Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
PIK3CB, PIK3R1
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
phosphatidylinositol-4/p110β/p85α/p110 beta/p85 alpha/5-bisphosphate 3-kinase
Human
His Tag
SDS
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