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Thermo Scientific™ Pierce™ Sulfo-NHS Crosslinker

Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.

$210.00 - $2,252.25

Specifications

Chemical Reactivity Carboxyl-to-Amine
Membrane Permeable Yes
Molecular Weight 217.13
PEGylated No
Spacer Arm Length
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

PI24510

 
thermo scientific™
24510
500mg Pack for $286.65

PI24520

 
thermo scientific™
24520
8 x 2mg Pack of 8 Each for $210.00

PI24525

 
thermo scientific™
24525
5g Each for $2,252.25
Description & Specifications

Specifications

Chemical Reactivity Carboxyl-to-Amine
Membrane Permeable Yes
Molecular Weight 217.13
PEGylated No
Spacer Arm Length
Storage Requirements Store as detailed on product information sheet.
Water Soluble Yes

Thermo Scientific™ Pierce Sulfo-NHS is pure N-hydroxysulfosuccinimide, the essential compound needed to prepare water-soluble, amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.

Highlights:

  • Forms an acyl amino ester with carboxyl groups when used with the EDC
  • Sulfo-NHS-activated molecule reacts efficiently with primary amines, resulting in stable amide bond
  • Allows for two-step EDC reactions between carboxyl- and amine-containing molecules
  • Sulfo-NHS-activated molecule can be stabilized by drying, allowing manufacture of amine-reactive probes and surfaces
  • Reactive groups: Sulfo-NHS
  • Reactive toward: amino groups (upon activation of carboxylates)