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Thermo Scientific™ Pierce™ Methyl-PEG-Amine Compounds


MA(PEG)n: methyl- and amine-capped polyethylene glycol compounds containing 4 to 24 PEG units; use for surface-modification and molecule-pegylation applications.

Manufacturer: thermo scientific™  26110

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Catalog No. PI26110

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Description & Specifications

Specifications

Capping Group Methyl
Chemical Reactivity Carboxyl (via EDC)
Cleavable No
Description Pierce MA(PEG)4
Formulation 4-unit ethyleneglycol functionalized with methyl and amine ends; pale liquid
Molecular Weight 207.27
PEGylated Yes
Quantity 100mg
Sufficient For 19mL of typical 1X (25mM) reaction solution
Spacer Arm Length 15.5Å

Thermo Scientific™ Pierce MA(PEG)n Compounds are methyl- and amine-terminated polyethylene glycol reagents, where n equals 4 to 24 PEG units, that are useful for a variety of surface-modification and molecule-pegylation applications.

MA(PEG)n compounds have the form Methyl-PEGn-Amine and are ideal for derivatizing surfaces and molecules with discrete numbers (n = 4, 8, 12, 24) of ethylene glycol groups. Use any amine-reactive chemistry (e.g., EDC or NHS ester) to PEGylate surfaces, proteins, or other molecules with a precise number of hydrophilic, nonimmunogenic PEG units.

Highlights:

  • Pure compounds of specific size ensure complete control of PEGylation
  • Straight-chain compounds with simple terminal primary amine
  • Adaptable to a variety of modification procedures

Recommended for:

  • PEGylate carboxylate or amine surfaces Add inert mass to proteins, immunogens, drug compounds and probes Improve solubility (decrease aggregation) of proteins or peptides without affecting function Protect proteins from proteolysis