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Thermo Scientific™ Pierce™ DSS Crosslinker

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

$104.78 - $221.35

Specifications

Chemical Reactivity Amine-to-Amine
Cleavable No
Description Pierce DSS
Formulation Disuccinimidyl suberate; powder solid
Membrane Permeable Yes
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

PI21555

 
thermo scientific™
PI21555
1g Pack for $221.35

PI21655

 
thermo scientific™
PI21655
50mg Pack for $104.78

PI21658

 
thermo scientific™
PI21658
8 x 2mg Each for $114.79
Description & Specifications

Specifications

Chemical Reactivity Amine-to-Amine
Cleavable No
Description Pierce DSS
Formulation Disuccinimidyl suberate; powder solid
Membrane Permeable Yes
Molecular Weight 368.34
PEGylated No
Spacer Arm Length 11.4Å
Water Soluble No

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

Highlights:

  • Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Crosslink oriented antibodies to Protein A or G agarose
  • Immobilize proteins onto amine-coated surfaces