Please login to your online account to display your discounted pricing

Thermo Scientific™ Pierce™ DSP Crosslinker

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Manufacturer: thermo scientific™  22586

 View more versions of this product

Catalog No. PI22586

  • / Each

Description & Specifications


Spacer Arm Length 12Å
Chemical Reactivity Amine-to-Amine
Water Soluble No
Description Pierce DSP (Lomant's Reagent)
Sufficient For 124mL of typical 1X (1mM) reaction solution, or approx. 25 uses at 2mg reagent per use
Formulation Dithiobis(succinimidylpropionate); powder solid
Membrane Permeable Yes
Quantity 50mg
PEGylated No
Cleavable Yes
Molecular Weight 404.42

Thermo Scientific™ Pierce DSP Crosslinker (Lomant's Reagent) is an amine-reactive crosslinker with NHS-ester reactive ends and a cleavable disulfide bond in its spacer arm.


  • Cleavable by reducing agents
  • Membrane-permeable
  • Acylate in aqueous or organic media within two minutes at room temperature
  • Four- to five-hour half-life of ester at pH 7.0
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups