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Thermo Scientific™ Pierce™ DSP Crosslinker

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Manufacturer:  Thermo Scientific™ PI22585

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Catalog No. PI22585


 

Specifications

Description

Thermo Scientific™ Pierce DSP Crosslinker (Lomant's Reagent) is an amine-reactive crosslinker with NHS-ester reactive ends and a cleavable disulfide bond in its spacer arm.

Highlights:

  • Cleavable by reducing agents
  • Membrane-permeable
  • Acylate in aqueous or organic media within two minutes at room temperature
  • Four- to five-hour half-life of ester at pH 7.0
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups
Description & Specifications

Specifications

Amine-to-Amine
Pierce DSP (Lomant's Reagent)
Yes
No
2473mL of typical 1X (1mM) reaction solution, or approx. 500 uses at 2mg reagent per use
No
Yes
Dithiobis(succinimidylpropionate); powder solid
404.42
1g
12Å