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Thermo Scientific™ Pierce™ DMP Crosslinker

Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.

Manufacturer:  Thermo Scientific™ PI21667

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Catalog No. PI21667


 

Specifications

Description

Thermo Scientific™ Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.

Highlights:

  • Water-soluble
  • Rapid reaction with amines at alkaline pH values (pH 8-10)
  • Amidine bond retains net charge character of protein
  • Reversible at high pH values
  • Reactive groups: imidoester (homobifunctional)
  • Reactive toward: amino groups
Description & Specifications

Specifications

Amine-to-Amine
Pierce DMP
Yes
No
3858mL of typical 1X (1mM) reaction solution, or approx. 500 uses at 2mg reagent per use
Yes
No
Dimethyl pimelimidate-2HCl; powder solid
259.17
1g
9.2Å