missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Pierce™ Cysteine-Reactive Tandem Mass Tag Reagents

Perform measurement of protein and peptide cysteine modifications (S-nitrosylation, oxidation and disulfide bridges) by multiplex quantitative mass spectrometry.

Manufacturer:  Thermo Scientific™ 90102

 View more versions of this product

Catalog No. PI90102


 

Specifications

Description

Perform measurement of protein and peptide cysteine modifications (S-nitrosylation, oxidation and disulfide bridges) by multiplex quantitative mass spectrometry with Thermo Scientific™ Pierce Cysteine-Reactive Tandem Mass Tag Reagents.


Additional Information and Online Ordering »

Tandem Mass Tag™ (TMT™) Reagents enable concurrent identification and multiplexed quantitation of proteins in different samples using tandem mass spectrometry. The iodoTMT™ Reagents are sets of isobaric (mass and structure) isomers that are iodoacetyl-activated for covalent, irreversible labeling of sulfhydryl (-SH) groups. Similar to iodoacetamide, iodoTMT Reagents react specifically with reduced cysteines (Cys) in peptides and proteins. IodoTMT Reagents can be differentiated by mass spectrometry (MS), enabling quantitation of the relative abundance of cysteine modifications, such as S–nitrosylation, oxidation and disulfide bonds, in cultured cells grown or treated with different conditions.

Highlights:

  • Specific – only reacts with sulfhydryl groups (reduced, unmodified cysteine residues)

  • Irreversible – labeled proteins and peptides are not susceptible to reducing agents

  • Flexible – options for duplex isotopic (MS) or sixplex isobaric (MS/MS) quantitation

  • Versatile – can be used to study cysteine modifications (e.g. di-sulfide bridges, S-nitrosylation)

Note:

IodoTMT Products replace our previously offered CysTMT Reagents, which utilized a dithiopyridine reactive group to reversibly label cysteine sulfhydryls.

Description & Specifications

Specifications

iodoTMTsixplex Label Reagent Set, 5 x 0.2mg
Set of -126 to -131 iodoTMT6 label reagents
5 sixplex (5 x 6-way) experiments
iodoTMT6-126 Label Reagent, 5 x 0.2mg
30 rxn kit
Promotions

Promotions

  • To make a purchase through the 2016 Thermo Scientific™ Mass Spec Rewards Program, select a combination of products from this list within and contact your local sales representative for a quote. Please mention the appropriate Promo Code from the table within.

    12/31/17