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Thermo Scientific™ Pierce™ BS(PEG)n Crosslinkers

Crosslink amines to amines with these long (21.7A and 35.8A) crosslinkers composed of NHS-ester groups and 5-unit or 9-unit PEG spacer arms that enhance protein solubility.

Manufacturer: thermo scientific™  21581

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Catalog No. PI21581

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Description & Specifications


Chemical Reactivity Amine-to-Amine
Cleavable No
Description Pierce BS(PEG)5
Formulation Bis(succinimidyl) penta(ethylene glycol); amber oil liquid
Membrane Permeable No
Molecular Weight x
PEGylated Yes
Quantity 100mg
Sufficient For 188mL of typical 1X (1mM) reaction solution, or approx. 50 uses at 2mg reagent per use
Spacer Arm Length 21.7
Storage Requirements Store desiccated at -20°C, equilibrate the vial to room temperature before opening.
Water Soluble Yes

Thermo Scientific™ Pierce BS(PEG)n Crosslinkers include BS(PEG)5 and BS(PEG)9, which are bis-succinimide ester-activated PEG compounds for crosslinking between primary amines in proteins and other molecules.


  • Water-soluble polyethylene glycol (PEG) spacer arm increases solubility of crosslinked proteins
  • Excellent choice for crosslinking cell surface proteins to stabilize protein interactions
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups