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Phospho-SYK (Y348) Mouse anti-Human, Mouse, APC, Clone: moch1ct, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $407.88

Specifications

Antigen Phospho-SYK (Y348)
Clone moch1ct
Host Species Murine
Gene Alias Spleen tyrosine kinase, p72-Syk
Applications Flow Cytometry (Intracellular Staining)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123201 Life Technologies
LS17901441
25 Tests Each for $170.28
501123202 Life Technologies
LS17901442
100 Tests Each for $407.88
Specifications

Description

This moch1ct monoclonal antibody recognizes human and mouse spleen tyrosine kinase (also known as SYK) when phosphorylated on tyrosine 348 (Y348). SYK is the founding member of the SYK family of kinases that also includes ZAP-70 (zeta-associated protein of 70 kD) and is expressed in hematopoietic cells, including B lymphocytes, immature (CD4, CD8 double-negative and double-positive) thymocytes, and myeloid cells, epithelial cell lines, and normal breast tissue. SYK is critical for B cell receptor (BCR) signaling and B cell development. Autophosphorylation of at Y348 is necessary for SYK to become fully catalytically active and creates a docking site for the SH2 domains of Vav, Grb2, p85 subunit of PI3 kinase, and PLC gamma.

Specificity of this moch1ct clone was confirmed by ELISA, flow cytometry, and western blotting.
Description & Specifications

Specifications

Phospho-SYK (Y348)
Murine
Flow Cytometry (Intracellular Staining)
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.06μg)/test
moch1ct
Spleen tyrosine kinase, p72-Syk
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer