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Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, PE, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $448.05

Specifications

Antigen Phospho-STAT6 (Y641)
Clone CHI2S4N
Host Species Mouse
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Species Reactivity Human, Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122405

 
affymetrix
12901342
100 tests Each for $448.05

501129321

 
affymetrix
12-9013-41
25 tests Each for $187.05
Description & Specifications

Specifications

Antigen Phospho-STAT6 (Y641)
Clone CHI2S4N
Host Species Mouse
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Species Reactivity Human, Mouse
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.