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Phospho-p38 MAPK (T180/Y182) Mouse anti-Human, PE, Clone: 4NIT4KK, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $433.55

Specifications

Antigen Phospho-p38 MAPK (T180/Y182)
Clone 4NIT4KK
Host Species Mouse
Gene Alias p38 mitogen-activated protein kinase, RK, CSBP
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122418

 
affymetrix
12907842
100 tests Each for $433.55

501129313

 
affymetrix
12-9078-41
25 tests Each for $187.05
Description & Specifications

Specifications

Antigen Phospho-p38 MAPK (T180/Y182)
Clone 4NIT4KK
Host Species Mouse
Gene Alias p38 mitogen-activated protein kinase, RK, CSBP
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

This 4NIT4KK monoclonal antibody recognizes human and mouse p38 mitogen-activated protein kinase (MAPK) when phosphorylated on T180/Y182. p38 MAPK belongs to a family of conserved serine/threonine protein kinases that are phosphorylated and activated in response to numerous stress stimuli including TLR ligands (such as LPS), osmotic shock, heat shock, UV irradiation, and inflammatory cytokines. There are four p38 MAPK members that include p38 alpha, p38 beta, p38 gamma, and p38 delta. The primary activators of p38 MAPK are MKK3/4 and MKK6. Several downstream targets of p38 MAPK have been identified including MK2/3, p53, ATF-2, and ETS1. p38 MAPK can be negatively regulated by the chemical inhibitor SB203580. Specificity of this 4NIT4KK clone was determined by ELISA, flow cytometry, and western blotting.