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Phospho-Histone H3 (S28) Rat anti-Human, Mouse, eFluor 660, Clone: HTA28, eBioscience™

Rat Monoclonal Antibody

$157.08 - $407.88

Specifications

Antigen Phospho-Histone H3 (S28)
Clone HTA28
Host Species Rat
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124499 Life Technologies
LS50912441
25 Tests Each for $157.08
501124500 Life Technologies
LS50912442
100 Tests Each for $407.88
Specifications

Description

The HTA28 monoclonal antibody recognizes phosphorylated serine 28 of human, mouse, rat, bovine, and hamster histone H3. This 15kDa protein is a component of eukaryotic chromatin that is involved in forming the nucleosome structure. Histone H3 can be phosphorylated at serine 10 and serine 28. Studies have demonstrated that phosphorylation at serine 28 is mediated by MSK1 following activation by the MAP kinase signaling pathway in response to tumor promoters (e.g., UV and EGF) and oncoproteins (e.g., c-Myc, c-Jun, and c-Fos). Histone H3 serine 28 phosphorylation has been linked to chromosome condensation during mitosis, cell transformation, and regulation of RNA polymerase III transcription machinery.
Description & Specifications

Specifications

Phospho-Histone H3 (S28)
Rat
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
HTA28
Flow Cytometry (Intracellular Staining)
eFluor 660
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test