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Alfa Aesar™ Phorbol 12-myristate 13-acetate, 99+%

Activates protein kinase C and promotes skin tumors in mice

$122.74 - $1,045.55

Chemical Identifiers

CAS 16561-29-8
Molecular Formula C36H56O8
Molecular Weight (g/mol) 616.836
MDL Number MFCD00036736
InChI Key PHEDXBVPIONUQT-RGYGYFBISA-N
Synonym phorbol 12-myristate 13-acetate, phorbol ester, 12-o-tetradecanoylphorbol-13-acetate, 12-o-tetradecanoylphorbol 13-acetate, factor a1, tetradecanoylphorbol acetate, 12-tetradecanoylphorbol 13-acetate, factor a1 croton oil, phorbol 13-acetate 12-myristate, phorbol-12-myristate-13-acetate
PubChem CID 27924
ChEBI CHEBI:37537
SMILES CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
View More Specs

Products 4
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ63916MCR View Documents Alfa Aesar™
J63916MCR
1mg Each for $122.74
 
AAJ63916LB0 View Documents Alfa Aesar™
J63916LB0
5mg Each for $306.88
 
AAJ63916MA View Documents Alfa Aesar™
J63916MA
10mg Each for $536.66
 
AAJ63916MB View Documents Alfa Aesar™
J63916MB
25mg Each for $1,045.55
 
Description

Description

Applications
PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

Solubility
Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.

Notes
Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Specifications

Chemical Identifiers

16561-29-8
616.836
PHEDXBVPIONUQT-RGYGYFBISA-N
27924
CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
C36H56O8
MFCD00036736
phorbol 12-myristate 13-acetate, phorbol ester, 12-o-tetradecanoylphorbol-13-acetate, 12-o-tetradecanoylphorbol 13-acetate, factor a1, tetradecanoylphorbol acetate, 12-tetradecanoylphorbol 13-acetate, factor a1 croton oil, phorbol 13-acetate 12-myristate, phorbol-12-myristate-13-acetate
CHEBI:37537

Specifications

Light Sensitive
1mg
C36H56O8
2407201
phorbol 12-myristate 13-acetate, phorbol ester, 12-o-tetradecanoylphorbol-13-acetate, 12-o-tetradecanoylphorbol 13-acetate, factor a1, tetradecanoylphorbol acetate, 12-tetradecanoylphorbol 13-acetate, factor a1 croton oil, phorbol 13-acetate 12-myristate, phorbol-12-myristate-13-acetate
CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
27924
616.83
≥99%
White
16561-29-8
MFCD00036736
14,7332
PHEDXBVPIONUQT-RGYGYFBISA-N
616.836
CHEBI:37537
Film or Powder
Phorbol 12-myristate 13-acetate
Safety and Handling

Safety and Handling

GHS H Statement
H315
Causes skin irritation.

GHS P Statement
P280-P264-P362-P321-P332+P313-P302+P352
Wear protective gloves/protective clothing/eye protection/face protection.
Wash thoroughly after handling.
Take off contaminated clothing and wash before reuse.
Specific treatment (see label).
If skin irritation occurs: Get medical advice/attention.
IF ON SKIN: Wash with plenty of soap and water.

Warning

RTECSNumber : QH4377000

Recommended Storage : −30° to −10°C