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Alfa Aesar™ Phorbol 12-myristate 13-acetate, 99+%

Activates protein kinase C and promotes skin tumors in mice

Manufacturer:  Alfa Aesar™ J63916MB

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Catalog No. AAJ63916MB



Description

Description

Applications
PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

Solubility
Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.

Notes
Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Specifications

Specifications

Phorbol 12-myristate 13-acetate
White
16561-29-8
MFCD00036736
14,7332
Very soluble in methanol,soluble in DMSO,chloroform,ethanol or acetone,ether,ethyl acetate,DMF or acetonitrile. Insoluble in water.
CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
27924
616.83
≥99%
Light sensitive
25mg
C36H56O8
2407201
12-o-tetradecanoylphorbol 13-acetate, 12-o-tetradecanoylphorbol-13-acetate, 12-tetradecanoylphorbol 13-acetate, factor a1, factor a1 croton oil, phorbol 12-myristate 13-acetate, phorbol 13-acetate 12-myristate, phorbol ester, phorbol-12-myristate-13-acetate, tetradecanoylphorbol acetate
PHEDXBVPIONUQT-RGYGYFBISA-N
616.836
CHEBI:37537
Film or Powder

Chemical Identifiers

16561-29-8
616.836
PHEDXBVPIONUQT-RGYGYFBISA-N
27924
CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
C36H56O8
MFCD00036736
12-o-tetradecanoylphorbol 13-acetate, 12-o-tetradecanoylphorbol-13-acetate, 12-tetradecanoylphorbol 13-acetate, factor a1, factor a1 croton oil, phorbol 12-myristate 13-acetate, phorbol 13-acetate 12-myristate, phorbol ester, phorbol-12-myristate-13-acetate, tetradecanoylphorbol acetate
CHEBI:37537
Safety and Handling

Safety and Handling

GHS H Statement
H315
Causes skin irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

RTECSNumber : QH4377000

TSCA : No

Recommended Storage : Store at -20°C

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