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Thermo Scientific™ Lab Vision™ PDGFRβ Ab-1, Rabbit Polyclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ PDGFRβ Ab-1, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1692PABX

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Catalog No. RB1692PABX

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Description & Specifications

Specifications

Antigen PDGFR, beta Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide derived from near the C-terminus of human PDGFR, beta
Isotype IgG
Quantity 1mL
Regulatory Status RUO
Research Discipline Growth Factor
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ PDGFRβ Ab-1, Rabbit Polyclonal Antibody.

PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and β coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, α while PDGF BB can bind and activate to both PDGFR, α and β.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not known.

Epitope: Near C-terminal

Immunogen: A synthetic peptide derived from near the C-terminus of human PDGFRβ

Molecular Weight: ∽190kDa

Postitive Control: Ovarian CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO