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Thermo Scientific™ Lab Vision™ PDGFRα Ab-1, Rabbit Polyclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1691PABX

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Catalog No. RB1691PABX

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Description & Specifications

Specifications

Antigen PDGFR, alpha Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha
Isotype IgG
Quantity 1mL
Regulatory Status RUO
Research Discipline Growth Factor
Type Primary
Monoclonal or Polyclonal Polyclonal
Target Species Human
Target Species Murine

Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and ß coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, α and β

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFRα

Molecular Weight: ∽190kDa

Postitive Control: Ovarian CA

Cellular Localization: Membrane Specific for PDGFR, α and does not react with PDGFR, β.

Recommended for:

  • Immunohistochemistry

Note:

USA: RUO; Int'l: RUO