Thermo Scientific™ Lab Vision™ PDGFRβ Ab-1, Rabbit Polyclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ PDGFRβ Ab-1, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RB1692P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ PDGFRβ Ab-1, Rabbit Polyclonal Antibody.PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and β coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, α while PDGF BB can bind and activate to both PDGFR, α and β.
Host Species: Rabbit
Species Reactivity: Human and Mouse. Others not known.
Epitope: Near C-terminal
Immunogen: A synthetic peptide derived from near the C-terminus of human PDGFRβ
Molecular Weight: ∽190kDa
Postitive Control: Ovarian CA
Cellular Localization: Membrane
- Immunohistochemistry (Formalin/paraffin)
USA: RUO; Int'l: RUO
|PDGFR, beta Ab-1|
|Ab without BSA/Azide (Frozen)|
|A synthetic peptide derived from near the C-terminus of human PDGFR, beta|