Thermo Scientific™ Lab Vision™ PDGFRα Ab-1, Rabbit Polyclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RB1691P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and ß coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, α and β
Host Species: Rabbit
Species Reactivity: Human, Mouse, and Rat. Others not known.
Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFRα
Molecular Weight: ∽190kDa
Postitive Control: Ovarian CA
Cellular Localization: Membrane Specific for PDGFR, α and does not react with PDGFR, β.
USA: RUO; Int'l: RUO
|PDGFR, alpha Ab-1|
|Ab without BSA/Azide (Frozen)|
|A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha|