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Thermo Scientific™ Lab Vision™ PDGFRα Ab-1, Rabbit Polyclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1691P1ABX

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Catalog No. RB1691P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen PDGFR, alpha Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha
Isotype IgG
Quantity 500µL
Regulatory Status RUO
Research Discipline Growth Factor
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and ß coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, α and β

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFRα

Molecular Weight: ∽190kDa

Postitive Control: Ovarian CA

Cellular Localization: Membrane Specific for PDGFR, α and does not react with PDGFR, β.

Recommended for:

  • Immunohistochemistry

Note:

USA: RUO; Int'l: RUO