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The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.Description & Specifications
DescriptionThe monoclonal antibody MH5A reacts with a homolog of PD-1 (PD-1H) also known as VISTA. PD-1H is a 309 aa type I transmembrane protein that belongs to the CD28 superfamily. This cell surface receptor is expressed on nearly all hematopoietic cells except B cells. VISTA negatively regulates T cell responses by suppressing early TCR activation, inhibiting cell proliferation, and suppressing TH1 cytokine production.
The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.
|Store at 2-8°C.|
|aqueous buffer, no sodium azide|