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PD-1H Armenian Hamster anti-Mouse, Clone: MH5A, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

$187.05 - $680.05

Specifications

Antigen PD-1H
Clone MH5A
Host Species Armenian Hamster
Gene Alias VISTA
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122965

 
affymetrix
16591982
100μg Each for $187.05

501122966

 
affymetrix
16591985
500μg Each for $680.05
Description & Specifications

Specifications

Antigen PD-1H
Clone MH5A
Host Species Armenian Hamster
Gene Alias VISTA
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The monoclonal antibody MH5A reacts with a homolog of PD-1 (PD-1H) also known as VISTA. PD-1H is a 309 aa type I transmembrane protein that belongs to the CD28 superfamily. This cell surface receptor is expressed on nearly all hematopoietic cells except B cells. VISTA negatively regulates T cell responses by suppressing early TCR activation, inhibiting cell proliferation, and suppressing TH1 cytokine production.

The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.