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Thermo Scientific™ Lab Vision™ Paxillin Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS404P1ABX

 View more versions of this product

Catalog No. MS404P1ABX


 

Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Host Species: Mouse

Clone: 5H11

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant full-length human paxillin protein

Molecular Weight: 68kDa

Positive Control: HeLa cells, Colon CA

Cellular Localization: Membrane and cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Paxillin Ab-1
Monoclonal
1mg/mL
Human,Rat
Ab without BSA/Azide (Frozen)
Purified recombinant full-length human paxillin protein
100μL
Cytoskeletal Protein
Monoclonal
Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
5H11
Unlabeled
Concentrated
Murine
IgG2a kappa
RUO
Primary
Human,Rat