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Thermo Scientific™ Lab Vision™ Paxillin Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS404P1ABX

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Catalog No. MS404P1ABX

  • / Each
 

Description & Specifications

Specifications

Regulatory Status RUO
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Cross Reactivity Human
Cross Reactivity Rat
Format Concentrated
Antigen Paxillin Ab-1
Immunogen Purified recombinant full-length human paxillin protein
Quantity 100µL
Clone 5H11
Isotype IgG2a kappa
Research Discipline Cytoskeletal Protein
Type Primary
Conjugate Unlabeled
Formulation Ab without BSA/Azide (Frozen)
Concentration 1mg/mL
Classification Monoclonal
Item Description 100uL; 1mg/mL; Purified w/o BSA, azide

Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Host Species: Mouse

Clone: 5H11

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant full-length human paxillin protein

Molecular Weight: 68kDa

Positive Control: HeLa cells, Colon CA

Cellular Localization: Membrane and cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO