Thermo Scientific™ Lab Vision™ Paxillin Ab-1, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS404P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Host Species: Mouse
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Purified recombinant full-length human paxillin protein
Molecular Weight: 68kDa
Positive Control: HeLa cells, Colon CA
Cellular Localization: Membrane and cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|Purified recombinant full-length human paxillin protein|
|Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting|