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PARP1 Mouse anti-Human, Clone: HLNC4, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $361.05

Specifications

Antigen PARP1
Clone HLNC4
Host Species Murine
Gene Alias poly ADP-ribose polymerase
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013510 Life Technologies
LS14666880
25μg Each for $216.05
5013511 Life Technologies
LS14666882
100μg Each for $361.05
Specifications

Description

This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.
Description & Specifications

Specifications

PARP1
Murine
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
HLNC4
poly ADP-ribose polymerase
Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL