Please login to your online account to display your discounted pricing

PARP1 Mouse anti-Human, Clone: HLNC4, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $361.05

Specifications

Antigen PARP1
Clone HLNC4
Host Species Mouse
Gene Alias poly ADP-ribose polymerase
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013510

 
affymetrix
14-6668-80
25μg Each for $216.05

5013511

 
affymetrix
14-6668-82
100μg Each for $361.05
Description & Specifications

Specifications

Antigen PARP1
Clone HLNC4
Host Species Mouse
Gene Alias poly ADP-ribose polymerase
Species Reactivity Human
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.