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PARP1 Mouse anti-Human, Clone: HC2R8, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $216.05

Specifications

Antigen PARP1
Clone HC2R8
Host Species Murine
Species Reactivity Human
Applications Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013508 Life Technologies
LS14666780
25μg Each for $129.05
5013509 Life Technologies
LS14666782
100μg Each for $216.05
Specifications

Description

This HC2R8 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HC2R8 antibody specifically recognizes both the cleaved and non-cleaved forms of PARP.
Description & Specifications

Specifications

PARP1
Murine
Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
HC2R8
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer