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The HC2R8 antibody specifically recognizes both the cleaved and non-cleaved forms of PARP.Description & Specifications
DescriptionThis HC2R8 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.
The HC2R8 antibody specifically recognizes both the cleaved and non-cleaved forms of PARP.
|Store at 2-8°C.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|