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PARP1 Mouse anti-Human, Clone: HC2R8, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $216.05

Specifications

Antigen PARP1
Clone HC2R8
Host Species Mouse
Species Reactivity Human
Applications Western Blotting
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013508

 
affymetrix
14-6667-80
25μg Each for $129.05

5013509

 
affymetrix
14-6667-82
100μg Each for $216.05
Description & Specifications

Specifications

Antigen PARP1
Clone HC2R8
Host Species Mouse
Species Reactivity Human
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This HC2R8 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HC2R8 antibody specifically recognizes both the cleaved and non-cleaved forms of PARP.