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PARP1 (Cleaved) Mouse anti-Human, PE, Clone: HLNC4, eBioscience™

Mouse Monoclonal Antibody

$245.05 - $404.55

Specifications

Antigen PARP1 (Cleaved)
Clone HLNC4
Host Species Mouse
Gene Alias poly ADP-ribose polymerase
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011101

 
affymetrix
12666841
25 tests Each for $245.05

5011102

 
affymetrix
12666842
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen PARP1 (Cleaved)
Clone HLNC4
Host Species Mouse
Gene Alias poly ADP-ribose polymerase
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary
Concentration 5μL (0.004μg)/test

This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.