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Thermo Scientific™ Lab Vision™ PARP (Poly ADP-Ribose Polymerase) Ab-3, Rabbit Polyclonal Antibody


Thermo Scientific™ PARP (Poly ADP-Ribose Polymerase) Ab-3, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  RB1680PABX

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Catalog No. RB1680PABX

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Description & Specifications

Specifications

Antigen PARP (Poly ADP-Ribose Polymerase) Ab-3
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide from the C-terminal region of bovine PARP
Isotype IgG
Quantity 1mL
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary

Thermo Scientific™ PARP (Poly ADP-Ribose Polymerase) Ab-3, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat and Cow. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminal region of bovine PARP

Molecular Weight: 116kDa

Positive Control: Raji cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO