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Thermo Scientific™ Lab Vision™ PARP (Poly ADP-Ribose Polymerase) Ab-2, Rabbit Polyclonal Antibody


Deliver accurate, reproducible results with the Thermo Scientific™ PARP (Poly ADP-Ribose Polymerase) Ab-2, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1516PABX

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Catalog No. RB1516PABX

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Description & Specifications

Specifications

Regulatory Status RUO
Antigen PARP (Poly ADP-Ribose Polymerase) Ab-2
Cross Reactivity Human
Cross Reactivity Mouse
Quantity 1mL
Host Species Rabbit
Applications Western Blotting
Immunogen A synthetic peptide for the N-terminal region of human PARP
Isotype IgG
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Research Discipline Apoptosis
Type Primary
Conjugate Unlabeled
Classification Polyclonal
Concentration 1mg/mL
Item Description 1mL; 1mg/mL; Purified w/o BSA, azide

Deliver accurate, reproducible results with the Thermo Scientific™ PARP (Poly ADP-Ribose Polymerase) Ab-2, Rabbit Polyclonal Antibody.

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide for the N-terminal region of human PARP

Molecular Weight: 116kDa

Positive Control: Raji cells, Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO