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PARP Mouse anti-Human, eFluor 450, Clone: HLNC4, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $448.05

Specifications

Antigen PARP
Clone HLNC4
Host Species Murine
Gene Alias poly ADP-ribose polymerase
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124193 Life Technologies
LS48666841
25 Tests Each for $201.55
501124194 Life Technologies
LS48666842
100 Tests Each for $448.05
Specifications

Description

This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.
Description & Specifications

Specifications

PARP
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
HLNC4
poly ADP-ribose polymerase
Flow Cytometry (Intracellular Staining)
eFluor 450
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.06μg)/test