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Pan Cytokeratin (AE1/AE3) Mouse, eFluor 615, Clone: AE1/AE3, eBioscience™

Mouse Monoclonal Antibody

$187.44 - $496.32


Antigen Pan Cytokeratin (AE1/AE3)
Clone AE1/AE3
Host Species Murine
Gene Alias keratin, basic, acidic
Species Reactivity Canine, Human, Monkey, Mouse, Rabbit, Rhesus Ma
View More Specs


For Research Use Only.

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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245827 Life Technologies
25μg Each for $187.44
50245828 Life Technologies
100μg Each for $496.32


The monoclonal antibodies AE1 and AE3 recognize many of the acidic and basic cytokeratin family members. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an alpha-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these proteins and their expression can help identify the origin of a neoplasm.

The AE3 monoclonal antibody recognizes the 65 to 67 triplet, 64, 59, 58, 56, 54 and 52kD proteins also known as cytokeratin 1, 2, 3, 4, 5, 6, 7, and 8 while the AE1 antibody recognizes 56.5, 54’, 50, 50’, 48, and 40kDa proteins (also known as CK10, 14, 15, 16 and 19). These antibodies can be used on a wide array of tissue samples from mouse, human, rat, primates (cynomolgus and rhesus), dog, cat, rabbit, and chicken.
Description & Specifications


Pan Cytokeratin (AE1/AE3)
Canine, Human, Monkey, Mouse, Rabbit, Rhesus Ma
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
keratin, basic, acidic
Immunocytochemistry,Immunohistochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen)
eFluor 615
Store at 2-8°C. Do not freeze. Light-sensitive material.