missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ p57 Kip2 Ab-7, Rabbit Polyclonal Antibody

Deliver accurate, reproducible results with the Thermo Scientific™ p57Kip2 Ab-7, Rabbit Polyclonal Antibody.

$280.47 - $1,427.10

Specifications

Antigen p57superscriptKip2superscript Ab-7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Bovine,Human,Mouse,Bovine,Human,Mouse
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
RB1637P Thermo Scientific™ Lab Vision™
RB1637P
Purified Ab with BSA and Azide 1mL Each for $1,313.29
RB1637P0 Thermo Scientific™ Lab Vision™
RB1637P0
Purified Ab with BSA and Azide 100μL Each for $280.47
RB1637P1 Thermo Scientific™ Lab Vision™
RB1637P1
Purified Ab with BSA and Azide 500μL Each for $774.20
RB1637P1ABX Thermo Scientific™ Lab Vision™
RB1637P1ABX
Ab without BSA/Azide (Frozen) 500μL Each for $873.12
RB1637PABX Thermo Scientific™ Lab Vision™
RB1637PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,427.10
RB1637R7 Thermo Scientific
RB1637R7
Ready-to-use for IHC (UVLP) 7mL Each for $771.06
Specifications

Description

Deliver accurate, reproducible results with the Thermo Scientific™ p57Kip2 Ab-7, Rabbit Polyclonal Antibody.

p57Kip2 (or CDKN1C) is a potent tight-binding inhibitor of several G1 cyclin complexes, and is a negative regulator of cell proliferation. The gene encoding human p57Kip2 is located on chromosome 11p15.5, a region implicated in both sporadic cancers, Wilm's tumor, and Beckwith-Wiedemann syndrome (BWS), a cancer syndrome, making it a tumor suppressor candidate. BWS is characterized by numerous growth abnormalities and an increased risk of childhood tumors. Several types of childhood tumors including Wilms' tumor, adrenocortical carcinoma and rhabdomyosarcoma display a specific loss of maternal 11p15 alleles, suggesting that genomic imprinting plays an important part. This region also contains two other imprinted genes, insulin-like growth factor II (IGF-II) and H19, both of which seem to be implicated in adrenal neoplasms.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Cow and Mouse. Others not known.

Epitope: Near C-terminus

Immunogen: A synthetic peptide from human p57Kip2 protein

Molecular Weight: 57kDa

Positive Control: Colon CA or placenta

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p57superscriptKip2superscript Ab-7
Polyclonal
Bovine,Human,Mouse,Bovine,Human,Mouse
RUO
Primary
IgG
Immunohistochemistry (Paraffin)
Unlabeled
Rabbit
Cancer and Tumor Biology
A synthetic peptide from human p57superscriptKip2superscript protein