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Thermo Scientific™ Lab Vision™ p57 Kip2 Ab-7, Rabbit Polyclonal Antibody

Deliver accurate, reproducible results with the Thermo Scientific™ p57Kip2 Ab-7, Rabbit Polyclonal Antibody.

$260.76 - $1,327.22

Specifications

Antigen p57superscriptKip2superscript Ab-7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Bovine
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

RB1637P

 
thermo scientific™ lab vision™
RB-1637-P
Purified Ab with BSA and Azide 1mL Each for $1,221.47

RB1637P0

 
thermo scientific™ lab vision™
RB-1637-P0
Purified Ab with BSA and Azide 100µL Each for $260.76

RB1637P1

 
thermo scientific™ lab vision™
RB-1637-P1
Purified Ab with BSA and Azide 500µL Each for $720.04

RB1637P1ABX

 
thermo scientific™ lab vision™
RB1637P1ABX
Ab without BSA/Azide (Frozen) 500µL Each for $811.94

RB1637PABX

 
thermo scientific™ lab vision™
RB1637PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,327.22

RB1637R7

 
thermo scientific
RB-1637-R7
Ready-to-use for IHC (UVLP) 7mL Each for $717.10
Description & Specifications

Specifications

Antigen p57superscriptKip2superscript Ab-7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Bovine
Cross Reactivity Human
Host Species Rabbit
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary
Immunogen A synthetic peptide from human p57superscriptKip2superscript protein
Isotype IgG

Deliver accurate, reproducible results with the Thermo Scientific™ p57Kip2 Ab-7, Rabbit Polyclonal Antibody.

p57Kip2 (or CDKN1C) is a potent tight-binding inhibitor of several G1 cyclin complexes, and is a negative regulator of cell proliferation. The gene encoding human p57Kip2 is located on chromosome 11p15.5, a region implicated in both sporadic cancers, Wilm's tumor, and Beckwith-Wiedemann syndrome (BWS), a cancer syndrome, making it a tumor suppressor candidate. BWS is characterized by numerous growth abnormalities and an increased risk of childhood tumors. Several types of childhood tumors including Wilms' tumor, adrenocortical carcinoma and rhabdomyosarcoma display a specific loss of maternal 11p15 alleles, suggesting that genomic imprinting plays an important part. This region also contains two other imprinted genes, insulin-like growth factor II (IGF-II) and H19, both of which seem to be implicated in adrenal neoplasms.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Cow and Mouse. Others not known.

Epitope: Near C-terminus

Immunogen: A synthetic peptide from human p57Kip2 protein

Molecular Weight: 57kDa

Positive Control: Colon CA or placenta

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)

Note:

USA: RUO; Int'l: RUO