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Thermo Scientific™ Lab Vision™ p53 Ab-6, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS187P1ABX

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Catalog No. MS187P1ABX

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Description & Specifications

Specifications

Antigen p53 Ab-6
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone DO-1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Murine
Immunogen Recombinant human wild-type p53 protein expressed in E. coli
Isotype IgG2a
Quantity 100μL
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Bovine
Target Species Human
Target Species Non-human Primate

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-1

Isotype: IgG2a

Species Reactivity: Human, Monkey and Cow. Reacts weakly with Mouse and Rat. Others not known.

Epitope: aa 11-25

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 cells or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry
  • Gel Supershift Assay

Note:

USA: RUO; Int'l: RUO