Thermo Scientific™ Lab Vision™ p53 Ab-6, Mouse Monoclonal Antibody
Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS187P1ABX
Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Host Species: Mouse
Species Reactivity: Human, Monkey and Cow. Reacts weakly with Mouse and Rat. Others not known.
Epitope: aa 11-25
Immunogen: Recombinant human wild-type p53 protein expressed in E. coli
Molecular Weight: 53kDa
Positive Control: SKBR-3 cells or MDA-231 cells, Colon CA
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
- Flow Cytometry
- Gel Supershift Assay
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|Flow Cytometry,Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting|
|Recombinant human wild-type p53 protein expressed in E. coli|