Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ p53 Ab-6, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS187P1ABX

 View more versions of this product

Catalog No. MS187P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen p53 Ab-6
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone DO-1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant human wild-type p53 protein expressed in E. coli
Isotype IgG2a
Quantity 100µL
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-1

Isotype: IgG2a

Species Reactivity: Human, Monkey and Cow. Reacts weakly with Mouse and Rat. Others not known.

Epitope: aa 11-25

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 cells or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry
  • Gel Supershift Assay

Note:

USA: RUO; Int'l: RUO