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Thermo Scientific™ Lab Vision™ p53 Ab-5, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-5, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS186P1ABX

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Catalog No. MS186P1ABX

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Description & Specifications

Specifications

Antigen p53 Ab-5
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone DO-7
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant human wild-type p53 protein expressed in E. coli
Isotype IgG2b kappa
Quantity 100µL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Type Primary

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-5, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Cow. Others not known.

Epitope: aa 37-45

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • Flow Cytometry