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Thermo Scientific™ Lab Vision™ p53 Ab-5, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-5, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS186P1ABX

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Catalog No. MS186P1ABX

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Description & Specifications

Specifications

Antigen p53 Ab-5
Regulatory Status IVD
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Format Concentrated
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2b kappa
Quantity 100µL
Immunogen Recombinant human wild-type p53 protein expressed in E. coli
Clone DO-7
Host Species Mouse
Formulation Ab without BSA/Azide (Frozen)
Research Discipline Cancer and Tumor Biology
Type Primary
Classification Monoclonal
Conjugate Unlabeled
Item Description 100uL; Purified w/o BSA, azide

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-5, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Cow. Others not known.

Epitope: aa 37-45

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • Flow Cytometry