Thermo Scientific™ Lab Vision™ p53 Ab-4, Mouse Monoclonal Antibody
Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS182P1ABX
Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Host Species: Mouse
Clone: PAb 122
Species Reactivity: Human, Monkey, Mouse, Rat, and Hamster. Others not known.
Epitope: aa 370-378
Immunogen: SV40-transformed mouse B4 cells
Molecular Weight: 53kDa
Positive Control: MDA-231 cells
Cellular Localization: Nuclear
- Western Blotting
- Immunoprecipitation (Denatured verified)
- Flow Cytometry
USA: RUO; Int'l: RUO
|SV40-transformed mouse B4 cells|
|Cancer and Tumor Biology|
|Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting|