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Thermo Scientific™ Lab Vision™ p53 Ab-4, Mouse Monoclonal Antibody

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS182P1ABX

 View more versions of this product

Catalog No. MS182P1ABX


 

Specifications

Description

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: PAb 122

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Mouse, Rat, and Hamster. Others not known.

Epitope: aa 370-378

Immunogen: SV40-transformed mouse B4 cells

Molecular Weight: 53kDa

Positive Control: MDA-231 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p53 Ab-4
Monoclonal
1mg/mL
Concentrated
SV40-transformed mouse B4 cells
100μL
Cancer and Tumor Biology
Monoclonal
Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting
PAb 122
Unlabeled
Murine
IgG2b kappa
RUO
Primary
Hamster,Human,Murine,Non-human Primate,Rat