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Thermo Scientific™ Lab Vision™ p53 Ab-4, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS182P1ABX

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Catalog No. MS182P1ABX

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Description & Specifications

Specifications

Antigen p53 Ab-4
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone PAb 122
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-Human Primate
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen SV40-transformed mouse B4 cells
Isotype IgG2b kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: PAb 122

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Mouse, Rat, and Hamster. Others not known.

Epitope: aa 370-378

Immunogen: SV40-transformed mouse B4 cells

Molecular Weight: 53kDa

Positive Control: MDA-231 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO