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Thermo Scientific™ Lab Vision™ p53 Ab-4, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS182P1ABX

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Catalog No. MS182P1ABX

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Description & Specifications

Specifications

Antigen p53 Ab-4
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone PAb 122
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-Human Primate
Cross Reactivity Rat
Format Concentrated
Host Species Murine
Immunogen SV40-transformed mouse B4 cells
Isotype IgG2b kappa
Quantity 100μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Hamster
Target Species Human
Target Species Murine
Target Species Non-human Primate
Target Species Rat

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-4, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: PAb 122

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Mouse, Rat, and Hamster. Others not known.

Epitope: aa 370-378

Immunogen: SV40-transformed mouse B4 cells

Molecular Weight: 53kDa

Positive Control: MDA-231 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO