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Thermo Scientific™ Lab Vision™ p53 Ab-1, Mouse Monoclonal Antibody

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS104P1ABX

 View more versions of this product

Catalog No. MS104P1ABX


 

Specifications

Description

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-1, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: PAb 240

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: aa 212-217

Immunogen: Murine p53 protein corresponding to aa 14-289

Molecular Weight: 53kDa

Positive Control: MDA-231 or SKBR-3 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Methacarn or formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p53 Ab-1
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG1
RUO
Primary
Human
Flow Cytometry,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
PAb 240
Unlabeled
Concentrated
Murine p53 protein corresponding to aa14-289
100μL
Cell Cycle
Monoclonal