Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ p53 Ab-1, Mouse Monoclonal Antibody


Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS104P1ABX

 View more versions of this product

Catalog No. MS104P1ABX

  • / Each
 

Description & Specifications

Specifications

Immunogen Murine p53 protein corresponding to aa14-289
Regulatory Status RUO
Isotype IgG1
Clone PAb 240
Applications Flow Cytometry
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Quantity 100µL
Host Species Mouse
Format Concentrated
Cross Reactivity Human
Antigen p53 Ab-1
Conjugate Unlabeled
Type Primary
Concentration 1mg/mL
Classification Monoclonal
Research Discipline Cell Cycle
Formulation Ab without BSA/Azide (Frozen)

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-1, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: PAb 240

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: aa 212-217

Immunogen: Murine p53 protein corresponding to aa 14-289

Molecular Weight: 53kDa

Positive Control: MDA-231 or SKBR-3 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Methacarn or formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO