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p21WAF1 Ab-6 Mouse Monoclonal Antibody, Epredia™
Achieve accurate, reproducible results with the Epredia™ p21WAF1 Ab-6, Mouse Monoclonal Antibody.
Supplier: Thermo Fisher Scientific MS454P1
Description
p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.Host Species: Mouse
Clone: HJ21; same as WA-1
Isotype: IgG1
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Human recombinant p21 protein
Molecular Weight: 21kDa
Positive Control: PC12, Ls174T or Raji cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Not suitable)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Not suitable)
- Flow Cytometry (Not Suitable)
Note:
USA: RUO; Int'l: RUO
Specifications
| p21WAF1 Ab-6 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Cancer and Tumor Biology | |
| Human, Rat | |
| IgG1 |
| Immunofluorescence, Western Blot | |
| HJ21; same as WA-1 | |
| Unconjugated | |
| Human recombinant p21 protein | |
| RUO | |
| Primary | |
| Concentrated |