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Thermo Scientific™ Lab Vision™ p21 WAF1 Ab-6, Mouse Monoclonal Antibody

Achieve accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-6, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS454P1ABX

 View more versions of this product

Catalog No. MS454P1ABX


 

Specifications

Description

Achieve accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-6, Mouse Monoclonal Antibody.

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: HJ21; same as WA-1

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: PC12, Ls174T or Raji cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Flow Cytometry (Not Suitable)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p21WAF1 Ab-6
Monoclonal
1mg/mL
Human,Rat
Murine
IgG1
RUO
Primary
Human,Rat
Immunofluorescence,Western Blotting
HJ21; same as WA-1
Unlabeled
Concentrated
Human recombinant p21 protein
100μL
Cancer and Tumor Biology
Monoclonal