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Thermo Scientific™ Lab Vision™ p21 WAF1 Ab-5, Mouse Monoclonal Antibody

Achieve accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-5, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS387P1ABX

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Catalog No. MS387P1ABX


 

Specifications

Description

Achieve accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-5, Mouse Monoclonal Antibody.

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: HZ52

Isotype: IgG1

Species Reactivity: Human, Cow, Mouse, and Rat. Others not known.

Epitope: Not determined

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Ls174T or Raji cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunoprecipitation
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p21superscriptWAF1superscript Ab-5
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG1
RUO
Primary
Bovine,Human,Rat
Immunohistochemistry (Paraffin),Immunoprecipitation
HZ52
Unlabeled
Concentrated
Full length human recombinant p21 protein
100μL
Cancer and Tumor Biology
Monoclonal