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Thermo Scientific™ Lab Vision™ p21 WAF1 Ab-11, Mouse Monoclonal Antibody

Ensure accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-11, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS891P1ABX

 View more versions of this product

Catalog No. MS891P1ABX


 

Specifications

Description

Ensure accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-11, Mouse Monoclonal Antibody.

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: CP74

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 1-80

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Raji, PC12 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p21superscriptWAF1superscript Ab-11
Monoclonal
1mg/mL
Concentrated
Full length human recombinant p21 protein
100μL
Cell Cycle
Monoclonal
Flow Cytometry,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
CP74
Unlabeled
Murine
IgG2b
RUO
Primary
Human,Rat