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Thermo Scientific™ Lab Vision™ p21 WAF1 Ab-11, Mouse Monoclonal Antibody


Ensure accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-11, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS891P1ABX

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Catalog No. MS891P1ABX

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Description & Specifications

Specifications

Antigen p21superscriptWAF1superscript Ab-11
Applications Flow Cytometry
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone CP74
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen Full length human recombinant p21 protein
Isotype IgG2b
Quantity 100µL
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary

Ensure accurate, reproducible results with the Thermo Scientific™ p21WAF1 Ab-11, Mouse Monoclonal Antibody.

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: CP74

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 1-80

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Raji, PC12 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO