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Thermo Scientific™ Lab Vision™ p130 Cas Ab-1, Mouse Monoclonal Antibody

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130Cas Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS855P1ABX

 View more versions of this product

Catalog No. MS855P1ABX


 

Specifications

Description

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130Cas Ab-1, Mouse Monoclonal Antibody.

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region p130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Host Species: Mouse

Clone: CAS-14; same as 35B-1A4

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant human p130Cas protein

Molecular Weight: 130kDa

Positive Control: MCF-7 Cells, HUVEC cells, Tonsil or breast CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

p130superscriptCassuperscript Ab-1
Monoclonal
1mg/mL
Human,Rat
Ab without BSA/Azide (Frozen)
Recombinant human p130superscriptCassuperscript protein
MCF-7 cells, HUVEC cells, tonsil or breast CA
RUO
Primary
Human,Rat
Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
CAS-14; same as 35B-1A4
Unlabeled
Concentrated
Murine
IgG2a kappa
100μL
Cell Cycle
Monoclonal