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Thermo Scientific™ Lab Vision™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody


Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS866P1ABX

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Catalog No. MS866P1ABX

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Description & Specifications

Specifications

Antigen p130/Rb2 Ab-2
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 130P215; same as DCS-215
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen A synthetic peptide from p130 corresponding to aa878-913
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.

Two retinoblastoma-related proteins, p107 and pRb2/p130 are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105). Like pRb they bind transforming proteins of DNA tumor viruses through a particular region called the “pocket domain”. Both proteins play a fundamental role in growth control. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.

Host Species: Mouse

Clone: 130P215; same as DCS-215

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 878-913

Immunogen: A synthetic peptide from p130 corresponding to aa 878-913

Molecular Weight: 130kDa

Positive Control: A427 cells, Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO