Thermo Scientific™ Lab Vision™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody
Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS866P1ABX
Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.Two retinoblastoma-related proteins, p107 and pRb2/p130 are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105). Like pRb they bind transforming proteins of DNA tumor viruses through a particular region called the “pocket domain”. Both proteins play a fundamental role in growth control. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.
Host Species: Mouse
Clone: 130P215; same as DCS-215
Species Reactivity: Human and Rat. Others not known.
Epitope: aa 878-913
Immunogen: A synthetic peptide from p130 corresponding to aa 878-913
Molecular Weight: 130kDa
Positive Control: A427 cells, Tonsil
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting|
|130P215; same as DCS-215|
|A synthetic peptide from p130 corresponding to aa878-913|