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Alfa Aesar™ p-Toluenesulfonyl isocyanate, 95%

Chemical Identifiers

Chemical Name or Material p-Toluenesulfonyl isocyanate
CAS 4083-64-1
Molecular Formula C8H7NO3S
Formula Weight 197.21g/mol
MDL Number MFCD00002030
UN Number UN2206
Beilstein 391287
Synonym Tosyl isocyanate
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA1749222

 
alfa aesar™
A17492-22
100g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAA1749236

 
alfa aesar™
A17492-36
500g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Melting Point 5°C
Boiling Point 144°C (10mmHg)
Quantity 100g
Flash Point 145°C (293°F)
Odor Irritating
Chemical Name or Material p-Toluenesulfonyl isocyanate
CAS 4083-64-1
Assay 95%
Molecular Formula C8H7NO3S
Formula Weight 197.21g/mol
MDL Number MFCD00002030
UN Number UN2206
Beilstein 391287
Synonym Tosyl isocyanate
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H334-H335-H315-H319
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
Health Hazard 3 GHS P Statement
P284a-P261-P280-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: ISOCYANATES, TOXIC, N.O.S.
RTECS Number DB9032000
TSCA TSCA

Applications
It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

Solubility
Reacts with water.

Notes
Keep away from alcohols, strong bases, amines, strong oxidizing agents.

Safety and Handling

Danger

GHS P Statement
P284a-P261-P280-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H334-H335-H315-H319
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.